SAMe 200 mg

Natural Factors SAMe provides a direct source of S-adenosyl-L-methionine, a naturally occurring compound found in every cell in the body. SAMe helps support mood balance through the synthesis of serotonin, dopamine, and phosphatidylserine, important mood-balancing compounds. It also helps relieve joint pain caused by osteoarthritis and contributes to numerous metabolic processes. This dual-action formula comes in easy-to-swallow, enteric-coated tablets that enhance its absorption and stability.
  • Supports healthy mood balance
  • Helps relieve the pain of osteoarthritis
  • Used to raise serotonin, dopamine, and phosphatidylserine levels
  • Assists with the production of sulfur compounds needed for healthy joint cartilage
SKU: 2707
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  • SAMe 200 mg, Natural Factors|v|image|2708
  • SAMe 200 mg, Natural Factors|v|image|2707
  • SAMe 200 mg, Natural Factors|v|image|2708
  • SAMe 200 mg, Natural Factors|v|image|2707
Key Ingredient

Quercetin

Quercetin is a natural plant pigment classified as a bioflavonoid. This key dietary antioxidant helps mitigate oxidative stress by scavenging and neutralizing free radicals in the body and improves the antioxidant activity of other dietary compounds such as vitamin C (Askari et al., 2021).
Powdered quercetin in a wooden bowl on a wooden tabletop

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Key Ingredient

Cranberry

For many people, these tart North American berries are too lip-puckering to eat fresh. Thankfully, cranberry extracts offer an even more concentrated source of antioxidants than their fresh counterparts.
Juicy fresh picked cranberries still on the brand sit on a wooden tabletop

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Key Ingredient

Echinacea

Echinacea, a popular flowering plant native to North America, is no stranger to health enthusiasts. Echinacea may be beautiful to look at, but did you know it also has a long list of health benefits?
Fresh picked and dried echinacea cone flowers sit on a wooden tabletop

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Key Ingredient

Licorice Root

Before it became a popular culinary ingredient, licorice was used as a medicine by ancient civilizations throughout Europe and Asia. 
Liquid, powdered, and fresh licorice root sit on a white countertop

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Key Ingredient

Milk Thistle

This Mediterranean herb with spiky purple flowers, named after its milky white veins, has been treasured for its healing properties since the first century AD.
Beautiful freshly picked purple milk thistle flowers sit in a wooden bowl

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Find out how adding Milk Thistle to your supplement regimen can support a healthy liver.

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Key Ingredient

Oregano

Oregano is no average herb. For fans of Mediterranean cuisine, oregano’s unique aroma and flavour are definitely recognizable, but did you know that it has a long list of health benefits, including antioxidant and anti-inflammatory benefits?
Dried oregano leaves alongside vibrant green fresh picked oregano on a wooden spoon

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Key Ingredient

Turmeric

Native to Southeast Asia, the brilliant yellow spice turmeric is a member of the ginger family. Arguably the best-known botanical today, the use of turmeric for both culinary and medicinal purposes dates back nearly 4,000 years.
Vibrant orange dried turmeric sits on a wooden spoon alongside fresh turmeric root in its natural form

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Key Ingredient

Pharma GABA

Gamma-aminobutyric acid, also simply known as GABA, has been clinically shown to be effective in helping soothe a racing mind.

A pile of powdered Pharma Gaba in a spoon sits on a wooden countertop

What is Pharma GABA®? 

Find out how adding this natural form of the calming brain compound gamma-aminobutyric acid to your supplement regimen can help support your mental health.  

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Key Ingredient

Wild Alaskan Salmon

Wild Salmon Oil delivers essential fatty acids just as nature intended.
Wild Alaskan salmon jump upstream in a pristine rushing Alaskan river

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What Else Should I Know?

Medicinal Ingredients

Each tablet contains:
S-adenosyl-L-methionine (SAMe) 200 mg
(from 400 mg of S-adenosyl-L-methionine disulfate tosylate)

Non-medicinal Ingredients

Microcrystalline cellulose, enteric coating (talc, shellac, glycerin, vegetable grade magnesium stearate (lubricant), silica, sodium alginate), stearic acid, vegetable grade magnesium stearate (lubricant), magnesium hydroxide. silica. calcium oxide.

Dosage

SAMe should always be taken an empty stomach SAMe must he taken for a minimum of 2 weeks, at which time effects should be observed. For mood balance: 1-4 tablets 2 times daily (up to 8 tablets daily) or as directed by a health care practitioner. Consult a health care practitioner for use beyond 6 weeks. For osteoarthritic pain: 2 tablets 3 times daily, not to exceed 6 tablets daily, or as directed by a health care practitioner. Consult a health care practitioner for use beyond 12 weeks.

Caution

Consult a health care practitioner prior to taking SAMe if you are taking anti-depressants, hepatotoxic drugs, or monoamine oxidase (MAO) inhibitors. Not recommended for use in children. Do not use if you are pregnant or breastfeeding or if you have bipolar disorder (manic-depressive illness). Do not take at night as SAMe may cause anxiety, restlessness, and insomnia. Possible side effects are mild gastrointestinal upsets (such as stomach pain, nausea, diarrhea, and flatulence), anxiety, hyperactive muscle movement, insomnia, and hypomania. When these side effects occur, they often diminish with time or resolve with lower doses or cessation of use. Keep out of the reach of children.

Allergy Information

Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, soy, corn, egg, fish, shellfish, salt, tree nuts, or GMOs. Suitable for vegetarians.

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